effects and benefits
Would you like to review the top three cholesterol-lowering
supplements that contain niacin?
enrolling niacin side effects, let’s talk a little bit about
comes in two basic forms—niacin (nicotinic acid) and
niacinamide (also called nicotinamide).
variation on vitamin B3, called inositol hexaniacinate, is
also available in supplements.
It has not
been linked with the usual vitamin B3
who need large amounts of b3, doctors used to recommend
Vitamin B3 is widely distributed in plant and animal foods.
The best food sources of vitamin B3 are peanuts, brewer’s
yeast, cereals, legumes, fish, and meat including liver.
Some vitamin B3 is also found in whole
side effects and dosage
part because it is added to white flour, most people
generally get enough vitamin B3 from their diets. Deficiency
is rare. However, 15 to 500 mg of this vitamin can be taken
as part of a multivitamin supplement or a B-complex. Larger
amounts are used for the treatment of various health
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Functions, Effects and Benefits: Vitamin B3 works with
vitamin B6, vitamin B1 and vitamin B2 to release energy from
carbohydrates. Therefore, these vitamins are often taken
together in a B-complex or multivitamin supplement (although
most B3 research uses nicotinic acid or niacinamide
needed to process alcohol and to form fat from
carbohydrates. Vitamin B3 niacin form also regulates
cholesterol, niacinamide does not. It increases HDL,
increases the ratio of HDL to cholesterol total (12%).
Medical Evidence: fairly strong.
to find out the top three cholesterol-lowering supplements
that contain vitamin B3 and lower cholesterol without side
effects of statins drugs.
acid and nicotinamide are rapidly absorbed from the stomach
or the intestine.
major form in the bloodstream, arises from enzymatic
hydrolysis of NAD (P) in the intestinal mucosa and liver,
and is transported to tissues that synthesize their own NAD
as needed. Vitamin B3 and NAD are biosynthesized from
dietary tryptophan via the kynurenine pathway and quinolinic
(Vitamin B3) Deficiency: Pellagra, the classic vitamin b3
deficiency disease, is rare in Western
include loss of appetite, bilateral dermatitis, skin rash,
diarrhea, mental changes, beefy tongue, and digestive and
emotional disturbance. Pellagra is often associated with a
largely cereal diet such as maize or sorghum and with other
micronutrient deficiency. Carcinoid syndrome or disturbed
tryptophan metabolism may also lead to
side effects (Vitamin B3) Clinical uses: Nicotinic acid (but
not nicotinamide) given as a drug in doses of 1.5-3 g/d
improves the blood cholesterol profile.
Side Effects - Vitamin B3 Toxicity - Niacin Overdose: Large
doses of nicotinic acid given to lower cholesterol may
produce flushing of the skin, hyperuricemia, and hepatic
abnormalities. These niacin side effects are reversed if the
drug is reduced in amount or discontinued. If these flushing
and other reactions to niacin side effects due to overdose
don't disappear, tell your doctor.
disease (inositol hexaniacinate)
High cholesterol (inositol
research: Hepatotoxic effects of alcohol may be counteracted
by ameliorating the redox state. Nicotinamide is under
investigation for helping prevent and control diabetes.
before using niacin contact a doctor in an attempt to avoid
these niacin side effects.